Nrosci/biosc 1070 And Nrosci 2070 Human Physiology (honors) Fall ...
NROSCI/BIOSC 1070 and NROSCI 2070
Human Physiology (Honors)
Fall Semester, 2008
Course Director
Bill Yates, Ph.D.
Office Hours:
Professor of Otolaryngology and Neuroscience
Monday from 2:30-4:00 PM
519 Eye and Ear Institute
Thursday from 4:00-5:00 PM
Office Phone: 647-9614
or by appointment
Cellular Phone: 889-0860
E-mail: byates@pitt.edu
Other Faculty
Kathleen Ryan, Ph.D.
Jennifer Woodward, Ph.D.
Associate Professor of Cell Biology & Physiology
Research Associate Professor of Surgery
Associate Director of Office of Medical Education
Administrative Director for Research and Academic
M-211 Scaife Hall
Affairs, Thomas E. Starzl Transplantation Institute
Phone: 648-8859
E1545 Starzl Biomedical Science Tower
E-mail: ryankath@medschool.pitt.edu
Phone: 383-8884
E-mail:woodwardje@upmc.edu
Alan Sved, Ph.D.
Professor and Chairman of Neuroscience
A210 Langley Hall
Phone: 624-6996
E-mail: sved@pitt.edu
Teaching Assistants
Angela Hattemer
E-mail: ash27@pitt.edu
Ashley Lafata
E-mail: lafata@pitt.edu
Kevin Yavorcik
E-mail: kjy5@pitt.edu
Class Meetings:
Lectures (1070 & 2070): Monday & Friday 4:30-5:45 PM
Langley A224
Lab and PBLs (1070 Only): Wednesday
3:30-5:25 PM
Benedum B63
Journal Club (2070 Only): Thursday
5:30-7:00 PM
241 Crawford
Textbook:
Guyton, A.C. and Hall, J.E. Textbook of Medical Physiology, 11th edn.
Elsevier, Amsterdam, 2006.
1070 Lab Manual: Pflanzer, R.G. Experimental Laboratory Physiology: Biopac Lab
Exercises. Kendall/Hunt, Dubuque, IA, 2004. (3 copies are on reserve
in Langley Library)
Web Site:
http://courseweb.pitt.edu/
Course is listed under NROSCI 1070
Course Reserve: A number of supplemental materials are on reserve in Langley Library.
They include the following supplemental reading for the Immunology
Section: Kindt, T.J., Osborne, B.A., and Goldsby, R.A. Kuby Immunology,
6th edn. Freeman, New York, 2007. ISBN: 1-4292-0211-4
Page 1
Grading: Your grade will be calculated as follows:
1070 & 2070: 20% from each of 4 exams
1070:
20% from assignments accompanying laboratories and problem-based
learning sessions.
2070:
20% from discussion of journal club articles and a written critical analysis of
one of those articles.
Exams will cover material presented in lectures and handouts. Although textbook readings
will not explicitly be covered on examinations, students are highly encouraged to at least skim
this material to provide a better understanding of information from lectures. Furthermore, the
textbook should be used as a reference while studying lecture notes and handouts and
preparing for problem based learning exercises.
It is expected that students will be fully-knowledgeable concerning basic principles of control
of cell function and membrane transport, which are covered in the prerequisites for this
course. Although this material will not be explicitly examined, students must fully understand
this information in order to comprehend the principles covered in this course. It is highly
recommended that all students review basic cell biology by studying Chapters 1-5 (pp. 3-71)
in the Guyton and Hall text.
Written assignments associated with laboratories and problem based learning sessions will be
due 1 WEEK following the lab or discussion. Although students are encouraged to use all
resources at their disposal (including the library, other students, and instructors) in completing
these assignments, answers must be written individually, without collaboration from
classmates.
If a legitimate reason (severe illness, etc.) prevents a student from taking an in-class exam or
turning in an assignment on the scheduled date, he or she must notify Dr. Yates in advance
and pre-arrange an alternate time to take the exam or turn-in the assignment. If arrangements
are not made BEFOREHAND, the student will receive a failing grade for the
exam/assignment.
Page 2
DATE
Topic
Lecturer
Reading
BLOCK 1 -- Cardiovascular/Muscle
25-Aug
Course Overview and Logistics; Cardiovascular 1
Yates
pp. 161-180
Monday
27-Aug
Muscle Contraction 1
Yates
pp. 72-91
Wednesday
Striated Muscle
29-Aug
Muscle Contraction 2
pp. 92-100 &
Yates
Friday
Smooth & Cardiac Muscle
103-106
1-Sep
Labor Day Holiday--No Class
Monday
3-Sep
1070: Laboratory # 1
TAs
pp. 1-41
Wednesday
Biopac Lab Exercises 1,2, & 3
4-Sep
2070: Journal Club # 1
Yates
Thursday
5-Sep
Control Mechanisms 1
Yates
pp. 748-760
Friday
Neural Mechanisms
8-Sep
Control Mechanisms 2
Yates
pp. 905-930
Monday
Endocrine Signaling
10-Sep
1070: Laboratory # 2
TAs
pp. 65-94
Wednesday
Biopac Lab Exercises 6-7 and 12 Lead ECG Handout
11-Sep
2070: Journal Club # 2
Yates
Thursday
12-Sep
Control Mechanisms 3
Yates
pp. 311-314
Friday
Integration
15-Sep
Cardiovascular 2
Yates
pp. 106-157 &
Monday
Cardiac Cycle/Electrical Events and ECG/Mechanical Aspects of Heart Pumping
269-277
17-Sep
1070: Laboratory # 3 and Overview of 9/24/08 PBL
TAs
pp. 95-129
Wednesday
Biopac Lab Exercises 8 & 9
18-Sep
2070: Journal Club # 3
Yates
Thursday
19-Sep
Cardiovascular 3
pp. 181-194 &
Yates
Friday
Cardiac Output and Capillary Exchange; Venous Return
232-245
22-Sep
Cardiovascular 4
Yates
pp. 195-203
Monday
Special Circulations and Control Mechanisms 1
24-Sep
1070: Problem Based Learning and Overview of 10/15/08 PBL
TAs
Wednesday
"Post Spaceflight Orthostatic Intolerance"
25-Sep
2070: Journal Club # 4
Sved
Thursday
26-Sep
Cardiovascular 5
Sved
pp. 204-231
Friday
Control Mechanisms 2 and Examples
29-Sep
Cardiovascular 6
pp. 258-268 &
Yates
Monday
Clinical Issues
278-288
1-Oct
EXAM # 1; 8/25 - 9/19 Lectures (Cardio 1-3/Muscle Contraction/Control Mechanisms)
Wednesday
BLOCK 2 --Respiration
3-Oct
Respiratory 1
Yates
pp. 419-428 &
Friday
Blood Composition, Clotting, Respiratory Mechanics
457-468
6-Oct
Respiration 2
Yates
pp. 471-490
Monday
Mechanics and Pulmonary Circulation
8-Oct
Respiration 3
Yates
pp. 491-533
Wednesday
Control Issues
10-Oct
Respiration 4
Yates
pp. 537-551
Friday
Clinical Aspects & REVIEW
Page 3
DATE
Topic
Lecturer
Reading
BLOCK 3 -- Renal
14-Oct
Renal 1
Sved
pp. 391-310
Tuesday
Functional Anatomy of the Kidney
15-Oct
1070: Problem Based Learning and Overview of the 10/22/08 PBL
TAs
Wednesday
Respiratory PBL
16-Oct
2070: Journal Club # 5
Yates
Thursday
17-Oct
Renal 2
Sved
Friday
Tubular Processing 1
pp. 312-326
20-Oct
Renal 3
Sved
pp. 327-364
Monday
Tubular Processing 2
22-Oct
1070: Problem Based Learning and Overview of the 11/5/08 PBL
TAs
Wednesday
Renal PBL # 1
23-Oct
2070: Journal Club # 6
Yates
Thursday
24-Oct
Renal 4
pp. 365-382 &
Sved
Friday
Regulation of Fluid Osmolarity/Control Mechanisms
402-415
BLOCK 4 -- Gastrointestinal & Metabolism
27-Oct
Gastrointestinal 1
Yates
pp. 771-790
Monday
Motility and Control
29-Oct
EXAM # 2; 9/22 - 10/10 Lectures (Cardio 4-6/Respiratory)
Wednesday
31-Oct
Gastrointestinal 2
Yates
pp. 791-818
Friday
Secretion and Absorption
3-Nov
Gastrointestinal 3
TBA
pp. 819-25 & 867-
Monday
Clinical Issues / Regulation of Appetite
74 & 961-77
5-Nov
1070: Problem Based Learning and Overview of the 11/12/08 PBL
TAs
Wednesday
Renal PBL 2
6-Nov
2070: Journal Club # 7
Yates
Thursday
pp. 865-67 & 881-
7-Nov
Gastrointestinal 4
Yates
88 & 931-60 & 383-
Friday
Metabolism and Acid-Base Balance
401
BLOCK 5 -- Immunology, Thermoregulation, and Growth Regulation
10-Nov
pp. 889-901 &
Temperature and Growth Regulation
Yates
Monday
978-995
12-Nov
1070: Problem Based Learning
TAs
Wednesday
"Drug Side Effects"
13-Nov
2070: Journal Club # 8
Yates
Thursday
14-Nov
Immunology 1
Woodward
Supplement
Friday
17-Nov
Immunology 2
Woodward
Supplement
Monday
19-Nov
EXAM # 3; 10/27 - 11/7 Lectures (Renal/Gastrointestinal)
Wednesday
Page 4
DATE
Topic
Lecturer
Reading
BLOCK 5 -- Immunology, Thermoregulation, and Growth Regulation, Cont.
21-Nov
Immunology 3
Woodward
Supplement
Friday
24-Nov
Immunology 4
Woodward
Supplement
Monday
26-Nov
Thanksgiving Holiday--No Class
— 30-Nov
BLOCK 6 -- Reproductive Physiology
1-Dec
Reproduction 1
Ryan
pp. 996-1010
Monday
Male Reproductive System
3-Dec
Reproduction 2
Ryan
pp. 1011-1026
Wednesday
Female Reproductive System
5-Dec
Reproduction 3
Ryan
pp. 1027-1041
Friday
Pregnancy and Contraception
13-Dec
EXAM # 4; 11/10 - 12/05 Lectures (Growth & Temperature
Saturday
Regulation/Immunology/Reproduction)
2:00-3:50 PM
Page 5
